Manually curated database containing a searchable list of approved peptide drugs and diagnostic agents. On these compounds, we have performed a detailed analysis of the structural features and collected information on their physicochemical and pharmacokinetic properties, indication, route of administration, production methodologies, marketing authorisation and origin of their design. The final purpose of this database is to aid the scientific community to more successfully design or pre-screen candidates at an early stage of the peptide drug discovery process.
We created a brief video tutorial to better understand how to exploit PepTherDia at its full potential.
[last updated on 03/10/2023]
Vera D’Aloisio, Paolo Dognini, Gillian A. Hutcheon, Christopher R. Coxon, PepTherDia: database and structural composition analysis of approved peptide therapeutics and diagnostics,
Drug Discovery Today, 2021, 26(6): 1409-1419, https://doi.org/10.1016/j.drudis.2021.02.019.
EaStChem School of Chemistry, University of Edinburgh, Edinburgh, UK