Angiotensin II

Therapeutic

Angiotensin II is a vasoconstrictor indicated for increasing blood pressure in adults with septic or other distributive shock

Structural features

SMILES

CC[C@@H]([C@@H](C(N[C@H](C(N1CCC[C@H]1C(N[C@H](C(O)=O)CC2=CC=CC=C2)=O)=O)CC3=CN=CN3)=O)NC([C@@H](NC([C@H](C(C)C)NC([C@@H](NC([C@H](CC(O)=O)N)=O)CCCNC(N)=N)=O)=O)CC4=CC=C(C=C4)O)=O)C

Sequence

DRVYIHPF

Molar mass

1046.197 g/mol

Constitutional members:

8

Natural amino acids

8

D-Amino acids

0

N-terminus

H

C-terminus

COOH

Cyclic

no

Members/cycle

N.A.

Bond to form cycle

N.A.

Lipidation

no

Glycosylation

no

Route of administration

IV

Terminal half-life

Plasma half-life < 1 min

Protein binding

-

Absorption and Bioavailability

References